The Only FDA Approved Topical to Treat Skin Texture

Tretinoin Cream, USP (Emollient) 0.05%

ReFissaTubeReFissa®’s 0.05% tretinoin concentration provides highest efficacy with lowest reaction threshold for reduction of fine lines, wrinkles, hyperpigmentation, and tactile roughness. The only FDA approved topical to treat skin texture, ReFissa is the only tretinoin product delivered in a soothing emollient cream easily tolerated by all skin types - even dry or sensitive skin. ReFissa utilizes the same active ingredient as other tretinoin treatments, but minimizes the reaction issues they often bring.

ReFissa Safety Information
ReFissa 0.05% is a prescription medicine that may reduce fine facial wrinkles and mottled hyperpigmentation in patients who also protect their skin from the sun and wear sunscreen daily. ReFissa does not eliminate wrinkles, repair sun damaged skin or reverse photo-aging. Do not use if you are pregnant, attempting pregnancy, or nursing. Do not use if taking medicines that may increase your sensitivity to sunlight. Use of ReFissa may make your skin more likely to burn from sunlight. ReFissa, early in treatment, may cause redness, itching, burning, stinging and peeling. If you have questions about side effects, contact your physician. If you are uncomfortable, use less medication and decrease the frequency of application. If discomfort is still significant, discontinue use and consult your physician. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1800-FDA-1088.

Please see full Prescribing Information and Patient Package Insert. ReFissa is a registered trademark of Suneva Medical, Inc. © 2013 Suneva Medical, Inc. All rights reserved.


SM 1356-07 REV00